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KMID : 0985520110160020154
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Korean Journal of Pancreas and Biliary Tract
2011 Volume.16 No. 2 p.154 ~ p.159
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A Case of Biliary Intraepithelial Neoplasia Presented with Recurrent Acute Pancreatitis
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Kim Dae-Yong
Park Sang-Hyun
Ahn Pyoung
Kim Yeon-Soo
Yoon Jai-Hoon
Suk Ki-Tae
Kim Jin-Bong
Choi Young-Hee
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Abstract
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Biliary intraepithelial neoplasia (BilIN) and intraductal papillary neoplasm of the biliary tract (IPN-B) were suggested the premalignant conditions of cholangiocarcinoma. BilIN microscopically manifests as flat, pseudopapillary or micropapillary lesions. In contrast, IPN-B is grossly visible, and is characterized by prominent papillary proliferation with distinct fibrovascular cores. A 65 years old woman was diagnosed the recurrent acute pancreatitis of uncertain etiology, 4 times, during the past 5 years. At the last admission, abdominal computed tomography revealed a tiny stone in the distal common bile duct. We performed an endoscopic retrograde cholangiopancreatography, and studies revealed a filling defect on distal CBD without evidence of CBD stone and a suspicious of soft tissue mass in the ampulla. We obtained biopsy specimens at the ampulla and distal CBD by biopsy forceps under the fluoroscopic guidance. The pathological report demonstrated BilIN. Therefore, we report a case of BilIN presented with recurrent acute pancreatitis with brief review.
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KEYWORD
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Biliary intraepithelial neoplasia, Recurrent acute pancreatitis
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